Liang F, Miller AS, Longerich S, Tang C, Maranon D, Williamson EA, Hromas R, Wiese C, Kupfer GM*, Sung P.  DNA requirement in FANCD2 deubiquitination by USP1-UAF1-RAD51AP1 in the Fanconi anemia DNA damage response.  Nature Communications, in press, 2020

 Liang Z, Liang F, Teng Y, Chen X, Liu J, Longerich S, Rao T, Green AM, Collins NB, Xiong Y, Lan L, Sung P, Kupfer GM. Binding of FANCI-FANCD2 Complex to RNA and R-Loops Stimulates Robust FANCD2 Monoubiquitination.  Cell Rep. 2019 Jan 15; 26(3): 564-572.e5.

Avila Figueroa A, Fasano JD, Martinez-Morilla S, Venkatesan S, Kupfer G, Hattangadi SM. miR181a regulates erythroid enucleation via the regulation of Xpo7 expression.  Haematologica. 2018 Mar 22. pii: haematol.2017.171785. doi:10.3324/haematol.2017.171785

Roth TL, Puig-Saus C, Yu R, Shifrut E, Carnevale J, Li PJ, Hiatt J, Saco J, Krystofinski P, Li H, Tobin V, Nguyen DN, Lee MR, Putnam AL, Ferris AL, Chen JW, Schickel JN, Pellerin L, Carmody D, Alkorta-Aranburu G, Del Gaudio D, Matsumoto H, Morell M, Mao Y, Cho M, Quadros RM, Gurumurthy CB, Smith B, Haugwitz M, Hughes SH, Weissman JS, Schumann K, Esensten JH, May AP, Ashworth A, Kupfer GM, Greeley SAW, Bacchetta R, Meffre E, Roncarolo MG, Romberg N, Herold KC, Ribas A, Leonetti MD, Marson A.  Reprogramming human T cell function and specificity with non-viral genome targeting. Nature. 2018 Jul; 559(7714): 405-409. doi: 10.1038/s41586-0180326-5. Epub 2018 Jul 11

Zhao W, Steinfeld JB, Liang F, Chen X, Maranon DG, Jian Ma C, Kwon Y, Rao T, Wang W, Sheng C, Song X, Deng Y, Jimenez-Sainz J, Lu L, Jensen RB, Xiong Y, Kupfer GM, Wiese C, Greene EC, Sung P. BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing. Nature. 2017 Oct 19; 550(7676): 360-365. doi: 10.1038/nature24060. Epub 2017 Oct 4

Liang F, Longerich S, Miller AS, Tang C, Buzovetsky O, Yong X, Maranon D, Wiese C, Kupfer GM, Sung P. Promotion of RAD51-mediated Homologous DNA Pairing by the RAD51AP1-UAF1 Complex.  Cell Reports. 2016; 15(10): 2016. doi: 10.1016/j.celrep.2016.05.007. Epub 2016 May 26

Chen X, Bosques L, Sung P, Kupfer GM. A novel role for non-ubiquitinated FANCD2 in response to hydroxyurea-induced DNA damage. Oncogene. 2015 Apr 20; 36(36):5220. doi: 

10.1038/onc.2017.238. Epub 2017 Jul 3

Longerich S, Kwon Y, Tsai MS, Hlaing AS, Kupfer GM and Sung P: Regulation of FANCD2 and FANCI monoubiquitination by their interaction and by DNA. Nucleic Acids Res. 2014 May 1;42 (9) :5657-70. Epub 2014 Mar 12. PMID: 24623813

Kupfer GM: Fanconi anemia: a signal transduction and DNA repair pathway. Yale J Biol Med. 2013 Dec 13;86 (4) :491-7. Epub 2013 Dec 13. PMID: 24348213

Chirnomas SD and Kupfer GM: The inherited bone marrow failure syndromes. Pediatr Clin North Am. 2013 Dec;60 (6) :1291-310. PMID: 24237972

Omer B, Kadan-Lottick NS, Roberts KB, Wang R, Demsky C, Kupfer GM, Cooper D, Seropian S and Ma X: Patterns of subsequent malignancies after Hodgkin lymphoma in children and adults. Br J Haematol. 2012 Sep;158 (5) :615-25. Epub 2012 Jul 6. PMID: 22775513

Lo SM, Choi M, Liu J, Jain D, Boot RG, Kallemeijn WW, Aerts JM, Pashankar F, Kupfer GM, Mane S, Lifton RP and Mistry PK: Phenotype diversity in type 1 Gaucher disease: discovering the genetic basis of Gaucher disease/hematologic malignancy phenotype by individual genome analysis. Blood. 2012 May 17;119 (20) :4731-40. Epub 2012 Apr 4. PMID: 22493294

Williams SA, Wilson JB, Clark AP, Mitson-Salazar A, Tomashevski A, Ananth S, Glazer PM, Semmes OJ, Bale AE, Jones NJ and Kupfer GM: Functional and physical interaction between the mismatch repair and FA-BRCA pathways. Hum Mol Genet. 2011 Nov 15;20 (22) :4395-410. Epub 2011 Aug 24. PMID: 21865299

Williams SA, Longerich S, Sung P, Vaziri C and Kupfer GM: The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI. Blood. 2011 May 12;117 (19) :5078-87. Epub 2011 Feb 25. PMID: 21355096

Song IY, Palle K, Gurkar A, Tateishi S, Kupfer GM and Vaziri C: Rad18-mediated translesion synthesis of bulky DNA adducts is coupled to activation of the Fanconi anemia DNA repair pathway. J Biol Chem. 2010 Oct 8;285 (41) :31525-36. Epub 2010 Jul 30. PMID: 20675655

Halene S, Gao Y, Hahn K, Massaro S, Italiano JE Jr, Schulz V, Lin S, Kupfer GM and Krause DS: Serum response factor is an essential transcription factor in megakaryocytic maturation. Blood. 2010 Sep 16;116 (11) :1942-50. Epub 2010 Jun 4. PMID: 20525922

Wilson JB, Blom E, Cunningham R, Xiao Y, Kupfer GM and Jones NJ: Several tetratricopeptide repeat (TPR) motifs of FANCG are required for assembly of the BRCA2/D1-D2-G-X3 complex, FANCD2 monoubiquitylation and phleomycin resistance. Mutat Res. 2010 Jul 7;689 (1-2) :12-20. Epub 2010 May 5. PMID: 20450923

Zhi G, Chen X, Newcomb W, Brown J, Semmes OJ and Kupfer GM: Purification of FANCD2 sub-complexes. Br J Haematol. 2010 Jul;150 (1) :88-92. Epub 2010 Apr 29. PMID: 20456353

Zhi G, Wilson JB, Chen X, Krause DS, Xiao Y, Jones NJ and Kupfer GM: Fanconi anemia complementation group FANCD2 protein serine 331 phosphorylation is important for fanconi anemia pathway function and BRCA2 interaction. Cancer Res. 2009 Nov 15;69 (22) :8775-83. Epub 2009 Oct 27. PMID: 19861535

Noy-Lotan S, Dgany O, Lahmi R, Marcoux N, Krasnov T, Yissachar N, Ginsberg D, Motro B, Resnitzky P, Yaniv I, Kupfer GM and Tamary H: Codanin-1, the protein encoded by the gene mutated in congenital dyserythropoietic anemia type I (CDAN1), is cell cycle-regulated. Haematologica. 2009 May;94 (5) :629-37. Epub 2009 Mar 31. PMID: 19336738

Green AM and Kupfer GM: Fanconi anemia. Hematol Oncol Clin North Am. 2009 Apr;23 (2) :193-214. PMID: 19327579

Collins NB, Wilson JB, Bush T, Thomashevski A, Roberts KJ, Jones NJ and Kupfer GM: ATR-dependent phosphorylation of FANCA on serine 1449 after DNA damage is important for FA pathway function. Blood. 2009 Mar 5;113 (10) :2181-90. Epub 2008 Dec 24. PMID: 19109555

Durkin SS, Guo X, Fryrear KA, Mihaylova VT, Gupta SK, Belgnaoui SM, Haoudi A, Kupfer GM and Semmes OJ: HTLV-1 Tax oncoprotein subverts the cellular DNA damage response via binding to DNA-dependent protein kinase. J Biol Chem. 2008 Dec 26;283 (52) :36311-20. Epub 2008 Oct 27. PMID: 18957425

Qi L, Cazares L, Johnson C, de Alarcon P, Kupfer GM and Semmes OJ: Serum protein expression profiling in pediatric Hodgkin lymphoma: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2008 Aug;51 (2) :216-21. PMID: 18421715

Mihaylova VT, Green AM, Khurgel M, Semmes OJ and Kupfer GM: Human T-cell leukemia virus I tax protein sensitizes p53-mutant cells to DNA damage. Cancer Res. 2008 Jun 15;68 (12) :4843-52. PMID: 18559532

Machida YJ, Machida Y, Chen Y, Gurtan AM, Kupfer GM, D'Andrea AD and Dutta A: UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation. Mol Cell. 2006 Aug;23 (4) :589-96. PMID: 16916645

Hussain S, Wilson JB, Blom E, Thompson LH, Sung P, Gordon SM, Kupfer GM, Joenje H, Mathew CG and Jones NJ:Tetratricopeptide-motif-mediated interaction of FANCG with recombination proteins XRCC3 and BRCA2. DNA Repair (Amst). 2006 May 10;5 (5) :629-40. Epub 2006 Apr 18. PMID: 16621732

Collins N and Kupfer GM: Molecular pathogenesis of Fanconi anemia. Int J Hematol. 2005 Oct;82 (3) :176-83. PMID: 16207587

Mi J and Kupfer GM: The Fanconi anemia core complex associates with chromatin during S phase. Blood. 2005 Jan 15;105 (2) :759-66. Epub 2004 Jul 15. PMID: 15256425

Qiao F, Mi J, Wilson JB, Zhi G, Bucheimer NR, Jones NJ and Kupfer GM: Phosphorylation of fanconi anemia (FA) complementation group G protein, FANCG, at serine 7 is important for function of the FA pathway. J Biol Chem. 2004 Oct 29;279 (44) :46035-45. Epub 2004 Aug 6. PMID: 15299017

Mi J, Qiao F, Wilson JB, High AA, Schroeder MJ, Stukenberg PT, Moss A, Shabanowitz J, Hunt DF, Jones NJ and Kupfer GM:FANCG is phosphorylated at serines 383 and 387 during mitosis. Mol Cell Biol. 2004 Oct;24 (19) :8576-85. PMID: 15367677

Thomashevski A, High AA, Drozd M, Shabanowitz J, Hunt DF, Grant PA and Kupfer GM: The Fanconi anemia core complex forms four complexes of different sizes in different subcellular compartments. J Biol Chem. 2004 Jun 18;279 (25) :26201-9. Epub 2004 Apr 13. PMID: 15082718